81377  München christian.haass(at)dzne.de +49 89 4400-46549 Areas of investigation/research focus Prof. Haass started to work on Alzheimer's disease (AD) hinein 1990 at a time, when very little welches known about the cellular mechanisms involved. Based on the pathology, which shows invariably the accumulation and deposition of Amyloid ß-peptide (Aß), he focused his work on the generation and metabolism of Aß. Christian Haass hypothesized against the widely accepted general opinion in this field that Aß may be produced from its precursor in a physiologically häufig pathway and not necessarily rein a pathological process. Indeed he found by using very simple tissue culture systems that Aß is produced and liberated under physiological conditions. This pivotal finding welches a major breakthrough for the entire field, since it allowed elucidating the molecular principles behind Aß generation as well as the identification of the enzymes (the so-called secretases) involved in generation and liberation of the peptide and finally the development of selective inhibitors to therapeutically lower Aß production in patients.
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We work on the molecular and cellular mechanisms of neurodegeneration with a strong focus on Alzheimer’s disease and related disorders. We are searching for therapeutic targets within the amyloid cascade. Secretases, amyloid metabolism and microglial function are within the focus of ur research.
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Leichte vierrädrige Straßen-Quads mit einer Nenndauerleistung/Nutzleistung von nicht mehr wie 4 kW ansonsten vierrädrige Leichtkraftfahrzeuge mit einer Nenndauerleistung/Nutzleistung von nicht eine größere anzahl als 6 kW, jeweilig mit nicht etliche denn zwei Sitzplätzen, einer durch die Bauart bestimmten Höchstgeschwindigkeit von nicht mehr wie 45 stundenkilometer, einer maximalen Leermasse von 425 kg des weiteren einem Fremdzündungsmotor mit einem Hubraum von nicht mehr als 50 cm³ oder einem Selbstzündungsmotor mit einem Hubraum von nicht etliche wie 500 zentimeter³ oder einer anderen Antriebsform.
Die netten Damen die immer an das Telefon umziehen sowie iwas nach aufklären ist sind Superbenzin freundlich ebenso hilfsbereit. Ich hatte Praxisunterricht bei omid außerdem auflage sagen wenn schon er war ein spitzenmäßiger Lehrer mit genug Beharrlichkeit je mich :2r
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